Microglial Activation States Trend 2026

In the brain, microglia are immune cells that shift between activation states, ranging from surveying to pro-inflammatory and repair-promoting phenotypes. This dynamic process is crucial for responding to injury or disease. Researchers study these states to understand neurological conditions like Alzheimer’s and multiple sclerosis. Ultimately, patients benefit from therapies targeting harmful activation while promoting protective functions, potentially slowing disease progression.